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Updated: May 3, 2026
Facile Preparation of 4-Substituted Quinazoline Derivatives
Published on: February 15, 2016
4-Chloro-3-methyl-phenyl quinoline-2-carboxyl-ate
E Fazal1, Manpreet Kaur2, B S Sudha1
1Department of Chemistry, Yuvaraja's College, Mysore 570 005, India.
Abstract:
In the title compound, C17H12ClNO2, the dihedral angle between the mean planes of the quinoline ring system and the benzene ring is 68.7 (7)°. The mean plane of the carboxyl-ate group is twisted from the latter planes by 14.0 (1) and 80.2 (4)°, respectively. In the crystal, weak C-H⋯O inter-actions are observed, forming chains along [001]. In addition, π-π stacking inter-actions [centroid-centroid distances = 3.8343 (13) and 3.7372 (13)Å] occur. No classical hydrogen bonds were observed.
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