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Biomarkers in growth.

Daniel J Raiten1, Ramkripa Raghavan, Klaus Kraemer

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Current growth assessments are inadequate. New biomarkers are needed to understand nutrition's impact on child development and long-term health outcomes.

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Area of Science:

  • Nutritional science
  • Biomarker development
  • Growth assessment

Background:

  • Existing anthropometric methods for assessing growth lack sensitivity and specificity.
  • Current methods do not fully elucidate the complex relationship between nutrition and growth.
  • There is a critical need for advanced tools to improve nutritional care and health programs.

Purpose of the Study:

  • To outline a roadmap for advancing the understanding of nutrition's role in growth.
  • To identify current gaps in the assessment of growth and nutrition.
  • To explore the potential of systems biology in evaluating the nutrition-growth relationship.

Main Methods:

  • Initiation of the Biomarkers in Growth (BIG) project, a program under the Biomarkers of Nutrition for Development (BOND) initiative.
  • Convening a session at the 20th International Congress on Nutrition.
  • Joint organization of the session by the BOND Secretariat and Sight and Life.

Main Results:

  • Discussion of current methodologies for evaluating growth, including linear growth and body composition.
  • Exploration of nutrition's impact on long-term health outcomes.
  • Consideration of systems biology approaches for a comprehensive assessment of the nutrition-growth nexus.

Conclusions:

  • A significant need exists for collaborative efforts to address knowledge gaps in growth biology and assessment.
  • The session underscored the importance of developing novel biomarkers for nutrition and growth.
  • Further research is required to enhance the understanding and evaluation of growth.