Native aortic valve endocarditis complicated by pseudoaneurysm of mitral-aortic intervalvular fibrosa

Filiz Ekici1, Abdullah Kocabaş, Doğukan Aktaş

  • 1Department of Pediatric Cardiology, Ankara Children's Hematology and Oncology Research and Training Hospital, Ankara, Turkey.

Insights

Pseudoaneurysm of the mitral-aortic intervalvular fibrosa (PA-MAIVF) is a rare endocarditis complication. In a child, PA-MAIVF led to rupture, cerebral embolism, and a fatal outcome.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Pediatric Cardiology

Background:

  • Native aortic valve endocarditis can lead to rare but severe complications.
  • The mitral-aortic intervalvular fibrosa (MAIVF) is a vulnerable region for infection and aneurysm formation.
  • Pseudoaneurysm of the mitral-aortic intervalvular fibrosa (PA-MAIVF) is a recognized, albeit infrequent, sequela.

Observation:

  • A 9-year-old boy with bicuspid aortic valve endocarditis developed a PA-MAIVF.
  • The PA-MAIVF was visualized using transthoracic echocardiography (2D and 3D).
  • Complications included cerebral embolism and hemorrhage.

Findings:

  • The PA-MAIVF ruptured into the pericardial space.
  • This rupture resulted in a fatal outcome for the patient.
  • Echocardiography proved effective in visualizing the PA-MAIVF and its rupture.

Implications:

  • PA-MAIVF requires prompt recognition and management in pediatric endocarditis cases.
  • Early diagnosis and intervention may be crucial to prevent catastrophic complications.
  • This case highlights the potential for rapid deterioration and mortality associated with PA-MAIVF.

Related Concept Videos

Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
1.8K
Aneurysm I: Introduction01:30

Aneurysm I: Introduction

An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
650
Endocarditis I: Introduction01:25

Endocarditis I: Introduction

Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
873
Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
1.6K
Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
1.0K
Mitral Valve Prolapse I: Introduction01:27

Mitral Valve Prolapse I: Introduction

IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...
1.1K