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Published on: March 31, 2023
Native aortic valve endocarditis complicated by pseudoaneurysm of mitral-aortic intervalvular fibrosa
Filiz Ekici1, Abdullah Kocabaş, Doğukan Aktaş
1Department of Pediatric Cardiology, Ankara Children's Hematology and Oncology Research and Training Hospital, Ankara, Turkey.
Abstract:
Pseudoaneurysm of mitral-aortic intervalvular fibrosa (PA-MAIVF) is a rare complication of native aortic valve endocarditis. This region is a relatively avascular area and prone to infection during endocarditis and subsequent aneurysm formation. The rupture into the pericardial cavity and left atrium or aorta, systemic embolism, myocardial infarction secondary to left coronary compression, and sudden death are the reported complications. Herein, we present a 9-year-old boy who was diagnosed with bicuspid aortic valve endocarditis complicated by PA-MAIVF, cerebral embolism, and hemorrhage. PA-MAIVF was visualized by both two- and three-dimensional transthoracic echocardiography and ruptured into pericardial space causing a fatal outcome.
Insights
Pseudoaneurysm of the mitral-aortic intervalvular fibrosa (PA-MAIVF) is a rare endocarditis complication. In a child, PA-MAIVF led to rupture, cerebral embolism, and a fatal outcome.
Area of Science:
- Cardiology
- Infectious Diseases
- Pediatric Cardiology
Background:
- Native aortic valve endocarditis can lead to rare but severe complications.
- The mitral-aortic intervalvular fibrosa (MAIVF) is a vulnerable region for infection and aneurysm formation.
- Pseudoaneurysm of the mitral-aortic intervalvular fibrosa (PA-MAIVF) is a recognized, albeit infrequent, sequela.
Observation:
- A 9-year-old boy with bicuspid aortic valve endocarditis developed a PA-MAIVF.
- The PA-MAIVF was visualized using transthoracic echocardiography (2D and 3D).
- Complications included cerebral embolism and hemorrhage.
Findings:
- The PA-MAIVF ruptured into the pericardial space.
- This rupture resulted in a fatal outcome for the patient.
- Echocardiography proved effective in visualizing the PA-MAIVF and its rupture.
Implications:
- PA-MAIVF requires prompt recognition and management in pediatric endocarditis cases.
- Early diagnosis and intervention may be crucial to prevent catastrophic complications.
- This case highlights the potential for rapid deterioration and mortality associated with PA-MAIVF.
Related Concept Videos
Mitral Stenosis I: Introduction
Aneurysm I: Introduction
Endocarditis I: Introduction
Aortic Regurgitation I: Introduction
Rheumatic Heart Disease I: Introduction
Mitral Valve Prolapse I: Introduction

