Related Experiment Video
Updated: May 3, 2026

Working with Human Tissues for Translational Cancer Research
Published on: November 26, 2015
Institutional review boards: what's old? What's new? What needs to change?
Sandra V Kotsis1, Kevin C Chung
1Ann Arbor, Mich. From the Section of Plastic Surgery, Department of Surgery, The University of Michigan Health System; and the University of Michigan Medical School.
Summary:
Institutional review boards have come under fire for being burdened with work, causing delays in the progress of human subject research without improvements in the protection of human subjects. Over the years, there have been increases in the numbers of clinical trials, the use of multisite studies, and the amount of bureaucracy, but there have been no changes to the system to accommodate these advancements. Proposed changes include the use of a centralized institutional review board for multisite studies and harmonization of reporting requirements among agencies. The purposes of this article are to review the history, structure, and purpose of the institutional review board, to assess the criticisms of the current system, and to discuss solutions for improvement.
More Related Videos
07:59Transition of Farm Pigs to Research Pigs using a Designated Checklist followed by Initiation of Clicker Training - a Refinement Initiative
Published on: August 21, 2021
08:55Translaminar Autonomous System Model for the Modulation of Intraocular and Intracranial Pressure in Human Donor Posterior Segments
Published on: April 24, 2020
Related Concept Videos
Ethics in Research
Drug Regulation
Drug Control Governance: Regulatory Bodies and Their Impact
Psychosurgery
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...
FDA Approved Drugs: Changes to Approved Drugs
Clinical Trials: Overview