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A pediatric case of cardiobacterium hominis endocarditis
Priyanka Suresh1, R Alexander Blackwood1
1Department of Pediatrics and Communicable Diseases, University of Michigan Medical School , Ann Arbor, MI, USA.
Insights
Gram-negative endocarditis in children is rare, often caused by HACEK bacteria. This case highlights Cardiobacterium hominis endocarditis in a pediatric patient with congenital heart disease, successfully treated with antibiotics.
Area of Science:
- Pediatric Cardiology
- Infectious Diseases
- Microbiology
Background:
- Gram-negative endocarditis is uncommon in pediatric populations.
- The HACEK group (Haemophilus species, Actinobacillus actinomycetemcomitans, Cardiobacterium hominis, Eikenella corrodens, Kingella kingae) are frequent causative agents.
- Cardiobacterium hominis endocarditis is particularly rare in children, with limited reported cases.
Observation:
- A 12-year-old boy with a history of Tetralogy of Fallot and pulmonary atresia presented with fatigue.
- Echocardiography revealed a vegetation on his right ventricle to pulmonary artery conduit.
- Blood cultures identified Cardiobacterium hominis as the causative pathogen.
Findings:
- The patient received a 6-week course of appropriate antibiotic therapy.
- Successful treatment of Cardiobacterium hominis endocarditis was achieved.
- This case adds to the limited pediatric literature on HACEK endocarditis.
Implications:
- Highlights the importance of considering HACEK organisms in pediatric endocarditis, especially in complex congenital heart disease.
- Emphasizes the need for prompt diagnosis and appropriate antibiotic management.
- Contributes to understanding the clinical presentation and treatment of rare pediatric infectious endocarditis.
Abstract:
Gram negative endocarditis is relatively rare in pediatrics but when they occur they are most frequently caused by one of the HACEK (Haemophilus species, Actinobacillus actinomycetemcomitans, C. hominis, Eikenella corrodens and Kingella kingae) group of microorganisms. Within the HACEK group of microorganisms there have been approximately 100 cases of Cardiobacterium hominis endocarditis reported in the literature, but only 2 previous cases of endocarditis and one case of pericarditis have been reported in children. In this report, we present a case of a 12-year-old boy with a right ventricle to pulmonary artery conduit for Tetralogy of Fallot with pulmonary atresia who presented at an annual cardiology examination with a 3 week history of fatigue and was found to have a vegetation on routine echocardiogram. Subsequent blood cultures grew Cardiobacterium hominis and the patient was treated successfully with 6 weeks of appropriate antibiotic therapy. We present this case and a review of the literature of the HACEK group of microorganisms in pediatrics.
Related Concept Videos
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Endocarditis II: Clinical Features of Infective Endocarditis
Endocarditis III: Medical Management
Endocarditis IV: Nursing Management
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