Related Experiment Video
Updated: May 3, 2026

An In Vitro Skin Irritation Test SIT using the EpiDerm Reconstructed Human Epidermal RHE Model
Published on: July 13, 2009
Patch test standard series recommended by the Brazilian Contact Dermatitis Study Group during the 2006-2011 period
Ida Alzira Gomes Duarte1, Greta Merie Tanaka2, Nathalie Mie Suzuki3
1Dermatology Clinic, School of Medicine, Fraternity of Santa Casa de São Paulo, São PauloSP, Brazil, MD, PhD in Medicine - Adjunct Professor at the School of Medicine, Santa Casa de São Paulo (FCMSCSP) and assistant at the Dermatology Clinic of the Fraternity of Santa Casa de São Paulo - São Paulo (SP), Brazil.
Abstract:
A retrospective study was carried out between 2006-2011. Six hundred and eighteen patients with suspected allergic contact dermatitis underwent the standard patch test series recommended by the Brazilian Contact Dermatitis Research Group. The aim of our study was to evaluate the variation of positive patch-test results from standard series year by year. The most frequently positive allergens were: nickel sulfate, thimerosal and potassium bichromate. Decrease of positive patch-test results over the years was statistically significant for: lanolin (p=0.01), neomycin (p=0.01) and anthraquinone (p=0.04). A follow-up study should be useful in determining which allergens could be excluded from standard series, as they may represent low sensitization risk.

