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Antigen-Capture Enzyme-Linked Immunosorbent Assay for Specific Detection of Mycoplasma pneumoniae
Published on: February 24, 2023
Mycoplasma genitalium: clinical significance and diagnosis
Vanda Plečko1, Lidija Zele Starčević, Vesna Tripković
1Assist. Prof. Vanda Plečko, MD, PhD, Department of Clinical and Molecular Microbiology, University Hospital Center Zagreb, Kišpatićeva 12, HR-10000 Zagreb, Croatia; vplecko@gmail.com.
Abstract:
Mycoplasma genitalium is considered the smallest self-replicating cell. It was first isolated in 1981, from 2 of 13 men with urethritis. Mycoplasma genitalium causes urethritis, cervicitis and pelvic inflammatory disease. Because of difficulties in cultivation, the diagnosis is based exclusively on PCR methodology. The recommended therapy for Mycoplasma genitalium infections is azithromycin or doxycycline. Development of macrolide resistance was shown to correlate with treatment failure.
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