Related Experiment Video
Updated: May 3, 2026

Metabolic Glycoengineering of Sialic Acid Using N-acyl-modified Mannosamines
Published on: November 25, 2017
Uptake of maleic hydrazide and related compounds into willow. A comparison between molecular structure and biological
1Botany Department, The University, Hull, England.
Abstract:
A study has been made of a range of maleic hydrazide (MH) derivatives to compare their molecular structures with what has already been found concerning MH behaviour in willow (Salix viminalis L.). Use was made of two properties of MH, one of which was the ability to become concentrated into root apices of young willow roots (Coupland and Peel, 1971); the other was the ability of MH to inhibit the uptake of uracil into the sieve elements in bark strip material (Coupland and Peel, 1972). As a result of the present investigations it appears that an unsaturated heterocyclic ring system, including the grouping-CH=CH-CO-NH- is essential to retain the characteristics of the MH molecule.
Related Concept Videos
Structure-Activity Relationships and Drug Design
SAR studies the intricate relationship between a drug's chemical structure and biological activity. It focuses on understanding how modifications to a drug's structure can influence...
Adrenergic Agonists: Chemistry and Structure-Activity Relationship
Aromatic ring substitutions: Substituting the aromatic ring with –OH groups at positions 3 and 4 yields catecholamines (e.g., epinephrine), which have a high affinity for adrenoceptors. Hydrogen bonding between –OH groups and receptors enhances adrenergic activity.
Separation of...
Nomenclature of Carboxylic Acid Derivatives: Acid Halides, Esters, and Acid Anhydrides
The IUPAC and common names of acid halides are derived from the corresponding carboxylic acids, by changing “ic acid” to “yl halide.” For example, as shown below, the IUPAC name ethanoyl chloride is derived from ethanoic acid, and the common name, acetyl chloride, is obtained from acetic acid.
Direct-Acting Cholinergic Agonists: Chemistry and Structure-Activity Relationship
The direct-acting...

