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Optimization of Antigen Preparation for Hemagglutination Inhibition Assay of Newcastle Disease Virus Serology

Optimization of Antigen Preparation for Hemagglutination Inhibition Assay of Newcastle Disease Virus Serology

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Hendra in the Hunter Valley.

K M Williamson^1,2, S Wheeler^1,2, J Kerr³

¹Hunter New England Population Health, Newcastle, NSW, Australia.

One Health (Amsterdam, Netherlands)

|October 29, 2020

Summary

This summary is machine-generated.

The first equine Hendra virus case in Australia's Hunter Valley prompted a swift health response and a 30-fold increase in horse vaccinations. This event highlights the need for One Health collaboration in managing zoonotic diseases.

Keywords:

Equine Hendra virus Henipaviruses Zoonosis

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Area of Science:

Veterinary Virology
Zoonotic Disease Epidemiology
One Health

Background:

Hendra virus poses a significant threat to equine and human health.
The Hunter Valley is a critical region for Australia's horse industry.
Previous Hendra virus outbreaks have primarily occurred in Queensland.

Purpose of the Study:

To document the first equine Hendra virus case in the Hunter Valley, New South Wales.
To describe the public health and biosecurity response to the detected case.
To assess the impact of the event on equine vaccination rates and identify potential virus reservoirs.

Main Methods:

Case detection and epidemiological investigation.
Biosecurity and contact tracing protocols.
Monitoring of flying fox populations (black and grey-headed flying foxes).
Analysis of equine vaccination uptake data.

Main Results:

The first confirmed equine Hendra virus case in the Hunter Valley occurred in June 2019.
No human or additional animal infections were reported following the initial case.
Equine vaccination uptake surged by over 30-fold in the region within three months.
Black and grey-headed flying foxes, known Hendra virus reservoirs, were identified in the area.

Conclusions:

The interagency response, involving human and animal health sectors, was crucial for managing the event.
The incident underscored the importance of ongoing surveillance and preparedness for Hendra virus.
Strengthening One Health partnerships is vital for future zoonotic disease outbreak responses.