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Published on: December 8, 2023
Boosting leukemia-specific T cell responses in patients following stem cell transplantation
Ute E Burkhardt1, Catherine J Wu2
1Department of Medical Oncology; Cancer Vaccine Center; Dana-Farber Cancer Institute; Boston, MA USA.
Abstract:
Whole tumor cell-based vaccines administered within the first 2 to 3 months after allogeneic stem cell transplantation stand out as a promising approach to enhance graft-vs.-leukemia responses. Herein, the implications of this finding for the development of strategies to improve the outcome of patients subjected to allogeneic stem cell transplantation are discussed.
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