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Detection of Modified Forms of Cytosine Using Sensitive Immunohistochemistry
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Detection of Modified Forms of Cytosine Using Sensitive Immunohistochemistry

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NCL-5D3: a new monoclonal antibody recognizing low molecular weight cytokeratins effective for immunohistochemistry

B Angus1, J Purvis, D Stock

  • 1University Department of Pathology, University of Newcastle upon Tyne, U.K.

The Journal of Pathology
|December 1, 1987
PubMed

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Immunocytochemistry and Immunohistochemistry01:22

Immunocytochemistry and Immunohistochemistry

Immunocytochemistry (ICC) and immunohistochemistry (IHC) are techniques that use antibodies to check for specific proteins or antigens in a sample. The technique was first published by Albert Coons in 1941 to detect the presence of pneumococcal antigen in tissue sections from mice infected with Pneumococcus. Immunocytochemistry helps localization of proteins or antigens in individual cells like blood cells, stem cells, etc., while immunohistochemistry does the same for tissue samples.
These...