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Updated: May 3, 2026

Modeling Spontaneous Metastatic Renal Cell Carcinoma mRCC in Mice Following Nephrectomy
Published on: April 29, 2014
[CCAFU Recommendations 2013: Renal cancer]
J-J Patard1, H Baumert, K Bensalah
1Membres experts du CCAFU.
Updated guidelines for renal cell carcinoma (RCC) emphasize updated imaging and minimally invasive treatments for localized disease. Advances in therapies are also noted for metastatic RCC.
Area of Science:
- Urology
- Oncology
Context:
- The CCAFU (Chinese Collaborative Anti-Cancer Foundation of Urology) renal sub-Committee previously established guidelines for renal cell carcinoma (RCC).
- Guidelines require regular updates to reflect advancements in diagnosis, treatment, and patient care.
Purpose:
- To update the 2010 CCAFU guidelines for renal cell carcinoma (RCC) diagnosis and management.
- To incorporate the latest evidence from systematic literature searches.
Summary:
- Multiphasic CT is the standard for renal tumor diagnosis.
- Percutaneous renal biopsies are crucial for localized RCC management.
- Partial nephrectomy is preferred for cT1 tumors; open surgery for advanced RCC.
- New treatments exist for metastatic RCC, with ongoing trials evaluating nephrectomy's role.
Impact:
- Provides updated, evidence-based recommendations for RCC management.
- Highlights the growing importance of conservative and minimally invasive approaches for localized RCC.
- Acknowledges the expanding therapeutic options for metastatic RCC.
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12:22The Use of Reverse Phase Protein Arrays RPPA to Explore Protein Expression Variation within Individual Renal Cell Cancers
Published on: January 22, 2013
06:38A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies
Published on: April 12, 2017
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