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Manic pseudo-delirium - two case reports

G Hutchinson1, A David2

  • 1Maudsley Hospital, London.

Behavioural Neurology
|February 4, 2014
PubMed

Insights

This study introduces Manic Pseudo-Delirium (MP-D), a subtype of bipolar disorder combining mania and delirium symptoms. It aims to improve recognition and understanding of this complex psychiatric presentation.

Area of Science:

  • Psychiatry
  • Neurology

Background:

  • Bipolar affective disorder is a primary diagnosis.
  • Delirium is typically not considered to co-exist with functional psychoses.
  • A subtype of bipolar disorder presents with features of both mania and delirium.

Purpose of the Study:

  • To report two cases illustrating a subtype of bipolar affective disorder.
  • To propose the term Manic Pseudo-Delirium (MP-D) for consistent recognition and characterization.
  • To explore potential explanations for MP-D to guide future research.

Main Methods:

  • Case report of two patients.
  • Extensive investigations to exclude underlying medical causes for delirium.
  • Clinical characterization of the proposed Manic Pseudo-Delirium subtype.

Main Results:

  • Two cases exhibiting a distinct presentation of bipolar affective disorder with concurrent manic and delirium features were identified.
  • The proposed Manic Pseudo-Delirium (MP-D) subtype integrates symptoms of both mania and delirium.
  • Medical causes for delirium were excluded in the reported cases.

Conclusions:

  • Manic Pseudo-Delirium (MP-D) is proposed as a distinct subtype of bipolar affective disorder.
  • This classification may aid in the consistent recognition and characterization of patients with combined manic and delirium symptoms.
  • Further research into the pathophysiology of MP-D is warranted to enhance understanding of both mania and delirium.
Keywords:
Brain diseasesDeliriumManic disorder

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