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Updated: May 3, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Implementing diagnostic reasoning to differentiate Todd's paralysis from acute ischemic stroke
1Emergency Department, Naval Hospital Guam, Agana Heights.
Emergency clinicians can avoid misdiagnosing stroke mimics like Todd's paralysis by using clinical reasoning. This involves gathering data, pausing for a diagnostic time-out, and ensuring the diagnosis matches findings, preventing errors from cognitive biases.
Area of Science:
- Neurology
- Emergency Medicine
- Cognitive Science
Background:
- Emergency departments face resource limitations, necessitating efficient diagnostic processes.
- Clinicians commonly use cognitive biases and heuristics for rapid diagnosis.
- These biases can lead to diagnostic errors in complex cases like stroke or stroke mimics.
Purpose of the Study:
- To highlight the diagnostic challenges in differentiating acute ischemic stroke from stroke mimics.
- To emphasize the role of clinical reasoning in overcoming cognitive biases.
- To propose a structured approach for accurate diagnosis in emergency settings.
Main Methods:
- Review of cognitive biases influencing emergency medicine diagnoses.
- Analysis of clinical presentation similarities between acute ischemic stroke and Todd's paralysis.
- Description of the clinical reasoning process: data gathering, diagnostic time-out, and data-reflective diagnosis.
Main Results:
- Cognitive biases (anchoring, availability, premature closure) can lead to misdiagnosis of stroke and stroke mimics.
- Todd's paralysis and acute ischemic stroke share overlapping symptoms, complicating differentiation.
- A structured clinical reasoning approach aids in accurate diagnosis.
Conclusions:
- Clinical reasoning is crucial for emergency clinicians to avoid diagnostic errors.
- Implementing a diagnostic time-out and data-driven diagnosis improves patient care.
- Distinguishing stroke from mimics like Todd's paralysis requires careful application of clinical reasoning.
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