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Updated: May 3, 2026

Semiconductor Sequencing for Preimplantation Genetic Testing for Aneuploidy
Published on: August 25, 2019
Second trimester ultrasound markers of fetal aneuploidy
Jiri Sonek1, Christopher Croom
1*Fetal Medicine Foundation, Dayton †Department of Obstetrics and Gynecology, Wright State University, Dayton, Ohio.
Abstract:
Although it is widely accepted that the best time to screen for chromosomal abnormalities is the first trimester, ultrasound evaluation of the fetus in the second trimester has also been shown to be useful for this purpose. A multitude of markers of varying strength has been developed over the past 30 years. In addition, the optimal time to diagnose fetal anomalies with confidence is also the mid second trimester. Therefore, performance of obstetrical ultrasound at this point in gestation continues to be an important component of prenatal care.
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