Related Experiment Video
Updated: May 3, 2026

Oromucosal as an Alternative Method for Administration of Cannabis Products in Rodents
Published on: August 22, 2025
Baclofen in the management of cannabis dependence syndrome
Bruce Imbert1, Nathalie Labrune2, Christophe Lancon2
1APHM, Sainte-Marguerite University Hospital, 270, bd sainte marguerite, Marseille 13274, France.
Abstract:
Cannabis is the most commonly used illicit drug in the world. However, only few studies have shown the efficacy of pharmacologic agents in targeting cannabis withdrawal symptoms or reducing the reinforcing effects of cannabis. Baclofen has been shown to reduce cannabis withdrawal symptoms and the subjective effects of cannabis. We think that the clinical utility of baclofen for cannabis dependence is a reasonable approach. A case report using baclofen is presented and provides preliminary support for the use of baclofen in the management of cannabis dependence.
Related Concept Videos
Chemotherapy-Induced Nausea and Vomiting: Cannabinoids
Two synthetic agonists of THC,...
Centrally Acting Muscle Relaxants: Therapeutic Uses
Centrally acting drugs are classified into spasmolytic and antispasmodic drugs. Spasmolytic drugs such as baclofen, diazepam, and tizanidine inhibit spinal motor neurons and decrease muscle tone. Spasmolytic drugs are administered for severe and chronic spasms due to multiple sclerosis, cerebral palsy, stroke, and spinal cord and muscle injuries. However,...
CNS Stimulants: Cocaine, Amphetamines and Cannabinoids
CNS Depressants: Barbiturates and Benzodiazepines
Drug Dependence
Skeletal Muscle Relaxants: Therapeutic Uses

