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[Paediatric Chagas in a non-endemic area]
Victoria Fumadó1, Teresa Juncosa2, Elizabet Posada3
1Servicio de Pediatría, Unidad de Medicina Importada, Hospital Universitari Sant Joan de Déu, Esplugues de Llobregat, Barcelona, España.
Enfermedades Infecciosas Y Microbiologia Clinica
|February 5, 2014
Summary
Chagas disease is an emerging pediatric concern in Spain due to immigration. Early screening and treatment of Trypanosoma cruzi infection in children and pregnant women are crucial for managing this preventable parasitic disease.
Area of Science:
- * Infectious Diseases
- * Parasitology
- * Public Health
Context:
- * Immigration is introducing new diseases, including Chagas disease, into Spain.
- * Chagas disease, caused by Trypanosoma cruzi, poses a risk to children and pregnant women from endemic regions.
- * Vertical transmission of Chagas disease from infected mothers to newborns is a significant concern.
Purpose:
- * To assess the prevalence of Chagas disease in immigrant children and newborns in Spain.
- * To evaluate the effectiveness of serological screening and benznidazole treatment for pediatric Chagas disease.
- * To highlight the importance of early detection and intervention for congenital and acquired Chagas disease.
Summary:
- * A study screened 202 immigrant children and newborns for Trypanosoma cruzi antibodies using ELISA and PCR.
- * 22 children (10.8%) were diagnosed with asymptomatic Chagas infection, including 5 congenital cases.
- * All infected children received benznidazole treatment, with some achieving serological negativity.
Impact:
- * Chagas disease is an important imported pediatric disease in Spain, preventable through timely screening.
- * Early diagnosis and treatment of Trypanosoma cruzi infection show promising results in children.
- * Routine screening of pregnant women and children from endemic areas is recommended for effective disease control.
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