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Bioenergetics of dihydrostreptomycin transport by Escherichia coli
S R Goss1, A B Spicer, W W Nichols
1Public Health Laboratory, John Radcliffe Hospital, Oxford, England.
FEBS Letters
|February 15, 1988
Abstract:
Previous demonstrations of the irreversibility of dihydrostreptomycin transport across the cytoplasmic membrane of Escherichia coli were not due to decreases in the magnitude of the cytoplasmic membrane potential (delta psi). Irreversibility was probably not due to ATP hydrolysis being coupled to transport, because the rate of energy-dependent dihydrostreptomycin uptake was unaffected by 10-fold reduction in the cellular ATP level.