Structural and functional bases of inhibited temperament

Jacqueline A Clauss1, April L Seay1, Ross M VanDerKlok2

  • 1Department of Psychiatry, Vanderbilt University Medical School, 1601 23rd Avenue South, Nashville, TN 37212, USA, Department of Clinical Psychology, Illinois School of Professional Psychology at Argosy University, 225 North Michigan Avenue, Chicago, IL 60601, USA, Department of Biostatistics, Middle Tennessee State University, 1301 E. Main St, Murfreesboro, TN 37132, USA, Department of Psychology, Vanderbilt University, 2301 Vanderbilt Place, Nashville, TN 37235, USA, Department of Radiology and Radiological Sciences, Vanderbilt University Medical School, 116 21st Avenue South, Nashville, TN 37203, USA, and Department of Pediatrics, Vanderbilt University Medical School, 2200 Children's Way, Nashville, TN 37232, USA.

Summary

Children with inhibited temperament show differences in brain structure, specifically larger amygdala and caudate volumes. These brain variations may increase the risk for psychiatric disorders like anxiety and depression.

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