Related Experiment Video
Updated: May 3, 2026
09:33
3D Imaging of PDL Collagen Fibers during Orthodontic Tooth Movement in Mandibular Murine Model
Published on: April 15, 2021
4.9K
Is pain duration associated with morphologic changes of osteoid osteomas at CT?
Sébastien Touraine1, Luciano Emerich, Damien Bisseret
1From the Department of Osteoarticular Radiology, Hôpital Lariboisière, AP-HP, 2 rue Ambroise Paré, 75475 Paris Cedex 10, France.
Radiology
|February 6, 2014
Summary
The nidus mineralization ratio of osteoid osteomas increases with pain duration, potentially indicating tumor age. Older patients may experience longer pain periods before treatment for these bone tumors.
Area of Science:
- Orthopedic imaging
- Bone pathology
- Radiology
Background:
- Osteoid osteomas are benign bone tumors characterized by pain.
- Computed tomography (CT) is crucial for diagnosing osteoid osteomas.
- Understanding morphologic changes in relation to clinical presentation is important.
Purpose of the Study:
- To evaluate morphologic changes of osteoid osteomas on CT scans.
- To assess the association between CT findings and pain duration in patients with osteoid osteomas.
Main Methods:
- Retrospective analysis of 96 patients with histopathologically proven osteoid osteomas.
- CT scans were analyzed for nidus characteristics including area, calcification, and mineralization ratio.
- Statistical analyses included ANOVA, Kaplan-Meier, and Cox regression to correlate findings with pain duration.
Main Results:
- Nidus mineralization ratio and patient age significantly increased with pain duration.
- Diaphyseal osteoid osteomas in long bones showed significantly lower mineralization.
- No significant association was found between pain duration and nidus area.
Conclusions:
- Nidus mineralization ratio may serve as a marker for osteoid osteoma age.
- Diaphyseal osteoid osteomas exhibit reduced nidus mineralization.
- Older patients may present with longer symptom duration before diagnosis.
Related Concept Videos
01:40Bone Remodeling
34.4K
Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
34.4K
01:31Osteoclasts in Bone Remodeling
3.9K
Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during...
3.9K
01:29Blood and Nerve Supply to the Bones
15.4K
Bones are dynamic organs that require a rich supply of oxygen and nutrients. Around 5% to 10% of the cardiac output supplies blood to the bones. A typical long bone has three main sources: the nutrient artery, the metaphyseal and epiphyseal arteries, and the periosteal arteries.
Nutrient Artery
The nutrient artery is the main blood vessel that enters the diaphysis via the nutrient foramen. While most long bones have only one nutrient foramen, large bones, such as the femur, may have two. This...
Nutrient Artery
The nutrient artery is the main blood vessel that enters the diaphysis via the nutrient foramen. While most long bones have only one nutrient foramen, large bones, such as the femur, may have two. This...
15.4K