Related Experiment Video
Updated: May 3, 2026
09:56
Intra-tracheal Administration of Haemophilus influenzae in Mouse Models to Study Airway Inflammation
Published on: March 2, 2016
10.0K
Multiple mycotic aneurysms infected with Haemophilus influenzae
Alexander F Nath1, Michael J Clarke1
1Northern Vascular Centre, Freeman Hospital, High Heaton, Newcastle Upon Tyne, United Kingdom.
Annals of Vascular Surgery
|February 6, 2014
Summary
This study reports the first known case of multiple mycotic aneurysms caused by Haemophilus influenzae. The successful treatment involved high-dose antibiotics and cryopreserved homografts.
Area of Science:
- Vascular Surgery
- Infectious Diseases
Background:
- Mycotic aneurysms are rare vascular infections often presenting treatment challenges.
- Haemophilus influenzae is an unusual pathogen for mycotic aneurysms.
Observation:
- Presents the first reported case of multiple mycotic aneurysms caused by Haemophilus influenzae.
- Details a patient with multiple aneurysms attributed to this specific bacterium.
Findings:
- Successful management achieved with high-dose antibiotics and cryopreserved homografts.
- Demonstrates the efficacy of this combined therapeutic strategy in a complex case.
Implications:
- Highlights a viable treatment option for rare multiple mycotic aneurysms.
- Suggests a potential management protocol for Haemophilus influenzae-related vascular infections.
Related Concept Videos
01:22Bacterial Meningitis I: Introduction
15
Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
15
01:26Bacterial Meningitis II: Pathophysiology
24
Bacterial meningitis typically begins when pathogens such as Neisseria meningitidis and Streptococcus pneumoniae colonize the nasopharynx and invade the bloodstream. This process is facilitated by bacterial virulence factors, such as polysaccharide capsules, which resist phagocytosis and complement-mediated killing. Less commonly, bacteria reach the central nervous system via contiguous spread from infections like otitis media or sinusitis, through congenital or acquired dural defects, or...
24
01:18Viral Meningitis
199
Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...
199
01:27Influenza
87
Influenza is an acute, highly communicable viral disease that affects the respiratory tract and is responsible for seasonal epidemics worldwide. Influenza A is the most prevalent type associated with widespread outbreaks and is subtyped based on two surface glycoproteins: hemagglutinin (H) and neuraminidase (N), as in H1N1. These glycoproteins are essential for viral infectivity, transmission, and immune recognition. Transmission occurs primarily through respiratory droplets and contaminated...
87
01:26Encephalitis ll: Pathophysiology
22
Encephalitis is inflammation of the brain parenchyma caused by direct viral invasion or immune-mediated mechanisms triggered by infections or tumors. Both processes lead to neuronal injury, disrupted neurotransmission, and diverse neurological symptoms, often with overlapping clinical and pathological features.Autoimmune EncephalitisIn autoimmune encephalitis, antibodies target neuronal antigens on cell surfaces, synapses, or within neurons. A key example is anti-NMDAR encephalitis, which can...
22
01:14Atypical Pneumonia
84
Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease...
84