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Mouse Models Of Helicobacter Infection And Gastric Pathologies
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A new mouse model of inflammation and gastric cancer
Thanh-Long M Nguyen1, Richard J Dipaolo1
1Department of Molecular Microbiology and Immunology; Saint Louis University School of Medicine; Saint Louis, MO USA.
Oncoimmunology
|February 6, 2014
Abstract:
Chronic inflammation increases the risk of developing several malignancies, including gastric cancer. A better understanding of how inflammation promotes gastric oncogenesis is therefore urgently needed. We have recently developed and characterized a mouse model that will be useful to elucidate the molecular and cellular circuitries bridging inflammation and gastric cancer.
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