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Updated: May 3, 2026

A Three-Dimensional Spheroid Model to Investigate the Tumor-Stromal Interaction in Hepatocellular Carcinoma
Published on: September 30, 2021
KIR/HLA immunogenetic background influences the evolution of hepatocellular carcinoma
Elisabetta Cariani1, Gabriele Missale2
1Clinical Pathology-Toxicology; Ospedale S Agostino-Estense; Modena, Italy.
Abstract:
Natural killer (NK) cells play a major role in antitumor immune responses. Recent results from our laboratory demonstrate the impact of the immunogenetic background on the activity of NK cells and hence on the outcome of hepatocellular carcinoma, disclosing perspectives for the development of NK-cell based therapies.
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