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Published on: June 15, 2019
Meningococcal septic shock after IUD insertion, a case presentation
Gina Romosan1, A Blidisel2, D Grigoras1
1University of Medicine and Pharmacy Victor Babes, Department of Obstetrics and Gynecology no.1, Timisoara, Romania.
Abstract:
Neisseria meningitidis is a normal commensal of human mucous membranes that is no longer considered to be restricted to the nasopharynx. Due to the practice of oral sex, the mucous membranes of the cervix, urethra or anus have become a potential infection site for this bacterium. Inserting an intrauterine device (IUD), can alter the protective barrier of the endocervical mucosa, allowing for bacterial infection and systemic spread. We present a case report of a 40-year-old woman who presented with abdominal pain, spotting and fever after inserting an IUD and developed a fulminant septic shock. Blood cultures and cultures from ascites showed the presence of Neisseria meningitidis group Y. From our knowledge, there are a few cases presented in the literature of toxic shock syndrome after IUD insertion, caused by Staphylococcus aureus or Streptococcus group A, but this is the first case of meningococcal sepsis after IUD insertion described. So, even though IUDs rarely cause significant infection, physicians should consider this device as a possible source in reproductive-age women with the clinical features of sepsis.
Insights
Neisseria meningitidis can cause severe sepsis after intrauterine device (IUD) insertion. This case highlights the risk of meningococcal infection in reproductive-age women with IUDs presenting with sepsis symptoms.
Area of Science:
- Infectious Diseases
- Gynecology
- Microbiology
Background:
- Neisseria meningitidis, a common bacterium, can colonize various mucosal sites beyond the nasopharynx, including the oral cavity and reproductive tract.
- Intrauterine devices (IUDs) can compromise the endocervical mucosal barrier, potentially facilitating bacterial invasion and systemic spread.
Observation:
- A 40-year-old woman developed severe septic shock with abdominal pain, spotting, and fever following IUD insertion.
- Blood and ascites cultures identified Neisseria meningitidis group Y as the causative agent.
Findings:
- This report details the first documented case of meningococcal sepsis following IUD insertion.
- While rare, IUDs can be associated with serious infections, including toxic shock syndrome, though typically caused by other bacteria like Staphylococcus aureus or Streptococcus.
Implications:
- Healthcare providers should consider IUDs as a potential source of infection in reproductive-age women presenting with sepsis symptoms.
- This case underscores the importance of recognizing less common pathogens in IUD-associated infections and prompt management to prevent severe outcomes.
Related Concept Videos
Bacterial Meningitis I: Introduction
Bacterial Meningitis II: Pathophysiology
Intrauterine Drug Delivery Systems
Endocarditis III: Medical Management
Brain Abscess l: Introduction
Endocarditis IV: Nursing Management

