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Differential changes in Aβ42 and Aβ40 with age

James Scott Miners1, Ruth Jones1, Seth Love1

  • 1Dementia Research Group, School of Clinical Sciences, University of Bristol, Frenchay Hospital, Bristol, UK.

Journal of Alzheimer'S Disease : JAD
|February 8, 2014
PubMed
Summary

As people age, soluble amyloid-beta (Aβ) peptide levels decrease while insoluble Aβ42 increases. This shift, particularly after age 50, may elevate Alzheimer

Keywords:
Aβ$_{40}$Aβ$_{42}$agingamyloid

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