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Updated: May 3, 2026

Microscopy of Fission Yeast Sexual Lifecycle
Published on: March 9, 2016
Sexual hormones in yeast
1Laboratory of Cell Biology, Faculty of Science, Osaka City University, Osaka.
Abstract:
Hormone-like substances were isolated from culture media of haploid strains of Saccharomyces cerevisiae. The one excreted by cells of mating type a made cells of the α type expand; the other, excreted by α type cells, made cells of the a type expand. Tentatively we call the former a hormone and the latter α hormone. The cell-expanding action of the a hormone was inhibited by actinomycin D, chloramphenicol and cycloheximide. The a hormone was shown to be heat-stable and dialyzable. Both hormones could be extracted with methylene chloride. The abilities of cells to produce these hormones and to respond to them are under control by the mating-type genes.
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