Related Experiment Video
Updated: May 3, 2026
06:48
A Multimodal Wide-Field Fourier-Transform Raman Microscope
Published on: December 30, 2025
875
CW-THz vector spectroscopy and imaging system based on 1.55-µm fiber-optics
Optics Express
|February 12, 2014
Summary
This study introduces a new terahertz (THz) spectroscopy system for rapid, stable measurements. The advanced system enables quick, non-destructive analysis of pharmaceutical cocrystals in tablets.
Area of Science:
- Physics
- Chemistry
- Engineering
Background:
- Terahertz (THz) spectroscopy offers unique material analysis capabilities.
- Existing THz systems often face limitations in speed, phase stability, and dynamic range.
- Accurate measurement of absorbance and relative permittivity is crucial for material characterization.
Purpose of the Study:
- To develop a continuous-wave (CW) terahertz (THz) vector spectroscopy and imaging system with enhanced performance.
- To achieve fast vector measurements with effective phase stabilization.
- To enable rapid, non-destructive analysis of pharmaceutical samples.
Main Methods:
- Utilized a 1.5-µm fiber optic uni-traveling-carrier photodiode and InGaAs photo-conductive receiver.
- Employed electro-optic (EO) phase modulators for THz phase control with shortened optical paths.
- Implemented simultaneous measurement of absorbance and relative permittivity.
Main Results:
- Achieved dynamic ranges of 100 dB·Hz at 300 GHz and 75 dB·Hz at 1 THz.
- Demonstrated excellent phase stability of 1.5° per minute.
- Successfully performed non-destructive analyses of pharmaceutical cocrystals within tablets in minutes.
Conclusions:
- The developed THz vector spectroscopy system offers high dynamic range and phase stability.
- The system enables rapid and non-destructive analysis of pharmaceutical formulations.
- This technology has potential applications in quality control and material science.
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