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Updated: May 3, 2026

Pre-clinical Evaluation of Tyrosine Kinase Inhibitors for Treatment of Acute Leukemia
Published on: September 18, 2013
Chronic myeloid leukemia treatment with Imatinib: An experience from a private tertiary care hospital
D C Doval1, Ullas Batra1, Sumit Goyal1
1Department of Medical Oncology and Research, Rajiv Gandhi Cancer Institute and Research Centre, Rohini, New Delhi, India.
Abstract:
The data presents 75 chronic myeloid leukemia patients diagnosed over a period 6 years i.e. from 2002 to 2008. The most common presentation was splenomegaly and 97% achieved complete hematological response at median duration of 4.3 weeks. The uniqueness of this study is follow-up with molecular response monitoring. Nearly, 30% patients achieved major molecular response (MMoR) by 12 months. 70% of patients achieved MMoR by median time of 60 months. Only 10% of the patient who achieved MMoR by 18 months had lost their responses subsequently.
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