Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Thyroid Gland01:23

The Thyroid Gland

7.9K
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
7.9K
Functions of Thyroid Hormones01:18

Functions of Thyroid Hormones

5.8K
The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
5.8K
Synthesis and Regulation of Thyroid Hormones01:20

Synthesis and Regulation of Thyroid Hormones

8.1K
Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
8.1K
Multiple Allele Traits01:49

Multiple Allele Traits

38.3K
The Concept of Multiple Allelism
38.3K
Multiple Regression01:25

Multiple Regression

4.0K
Multiple regression assesses a linear relationship between one response or dependent variable and two or more independent variables. It has many practical applications.
Farmers can use multiple regression to determine the crop yield based on more than one factor, such as water availability, fertilizer, soil properties, etc. Here, the crop yield is the response or dependent variable as it depends on the other independent variables. The analysis requires the construction of a scatter plot...
4.0K
Multiple Voltage Sources01:25

Multiple Voltage Sources

1.8K
Generally, a single battery is not enough to power some devices. In such cases, batteries can be combined in two ways: in series or in parallel.
In series, the positive terminal of one battery is connected to the negative terminal of another battery. Hence, the voltage of each battery is added to give the net voltage, which is increased because each battery boosts the electrons that enter it. The same current flows through each battery because they are connected in series.
Batteries are...
1.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Integrating CAR-T cells with other immunotherapies for improved efficacy in cancer patients.

Current research in translational medicine·2025
Same author

Consensus Statements for Clinical Practice in Advanced/Metastatic Colorectal Cancers in India Using a Modified Delphi Method.

South Asian journal of cancer·2025
Same author

Liquid Biopsy and Colorectal Cancer.

South Asian journal of cancer·2025
Same author

Current Issues of Next-Generation Sequencing-Based Circulating Tumor DNA Analysis in Colorectal Cancer.

South Asian journal of cancer·2025
Same author

Patterns of Care, Prognostic Factors, and Survival Outcomes for Patients of Cervical Carcinoma: A Study From North India.

Cureus·2024
Same author

Treatment pattern and outcomes of leptomeningeal carcinomatosis in India - a retrospective study.

The Lancet regional health. Southeast Asia·2024
Same journal

Gastric Teratoma: An Unusual Presentation and Location.

Indian journal of medical and paediatric oncology : official journal of Indian Society of Medical & Paediatric Oncology·2018
Same journal

Macrodystrophia Lipomatosa: Clinico-patho-radiological Correlation.

Indian journal of medical and paediatric oncology : official journal of Indian Society of Medical & Paediatric Oncology·2018
Same journal

A Case of Multifocal Eosinophilic Granuloma Involving Spine and Pelvis in a Young Adult: A Radiopathological Correlation.

Indian journal of medical and paediatric oncology : official journal of Indian Society of Medical & Paediatric Oncology·2018
Same journal

Flagellate Rash: An Unusual Complication of Bleomycin Therapy - A Case Report with Brief Review of Literature.

Indian journal of medical and paediatric oncology : official journal of Indian Society of Medical & Paediatric Oncology·2018
Same journal

Primary Renal Cell Lymphoma: Case Report, Diagnosis, and Management.

Indian journal of medical and paediatric oncology : official journal of Indian Society of Medical & Paediatric Oncology·2018
Same journal

Ewing's Sarcoma of the Calcaneum.

Indian journal of medical and paediatric oncology : official journal of Indian Society of Medical & Paediatric Oncology·2018
See all related articles

Related Experiment Video

Updated: Feb 15, 2026

An Organotypic High Throughput System for Characterization of Drug Sensitivity of Primary Multiple Myeloma Cells
09:41

An Organotypic High Throughput System for Characterization of Drug Sensitivity of Primary Multiple Myeloma Cells

Published on: July 15, 2015

9.1K

Multiple Myeloma Presenting as Thyroid Plasmacytoma.

Kaalindi Singh1, Pankaj Kumar1, Ritesh Pruthy2

  • 1Department of Radiation Oncology, Max Super Speciality Hospital, Mohali, Punjab, India.

Indian Journal of Medical and Paediatric Oncology : Official Journal of Indian Society of Medical & Paediatric Oncology
|January 16, 2018
PubMed
Summary
This summary is machine-generated.

Multiple myeloma rarely infiltrates the thyroid gland. This case highlights a patient initially diagnosed with extramedullary thyroid plasmacytoma, later confirmed as multiple myeloma with thyroid involvement.

Keywords:
Extramedullary plasmacytomamultiple myelomasolitary bone plasmacytomathyroid gland

More Related Videos

Interphase Fluorescence in situ Hybridization of Bone Marrow Smears of Multiple Myeloma
07:53

Interphase Fluorescence in situ Hybridization of Bone Marrow Smears of Multiple Myeloma

Published on: April 15, 2022

4.8K
Establishment of a Human Multiple Myeloma Xenograft Model in the Chicken to Study Tumor Growth, Invasion and Angiogenesis
10:04

Establishment of a Human Multiple Myeloma Xenograft Model in the Chicken to Study Tumor Growth, Invasion and Angiogenesis

Published on: May 1, 2015

13.5K

Related Experiment Videos

Last Updated: Feb 15, 2026

An Organotypic High Throughput System for Characterization of Drug Sensitivity of Primary Multiple Myeloma Cells
09:41

An Organotypic High Throughput System for Characterization of Drug Sensitivity of Primary Multiple Myeloma Cells

Published on: July 15, 2015

9.1K
Interphase Fluorescence in situ Hybridization of Bone Marrow Smears of Multiple Myeloma
07:53

Interphase Fluorescence in situ Hybridization of Bone Marrow Smears of Multiple Myeloma

Published on: April 15, 2022

4.8K
Establishment of a Human Multiple Myeloma Xenograft Model in the Chicken to Study Tumor Growth, Invasion and Angiogenesis
10:04

Establishment of a Human Multiple Myeloma Xenograft Model in the Chicken to Study Tumor Growth, Invasion and Angiogenesis

Published on: May 1, 2015

13.5K

Area of Science:

  • Oncology
  • Endocrinology
  • Pathology

Background:

  • Multiple myeloma (MM) is a plasma cell malignancy.
  • Extramedullary involvement, particularly in the thyroid, is uncommon in MM.

Observation:

  • A patient presented with hoarseness and a thyroid lesion involving cartilage.
  • Initial diagnostics ruled out MM, suggesting extramedullary plasmacytoma of the thyroid.

Findings:

  • Subsequent imaging revealed bone lesions, leading to a diagnosis of MM with thyroid infiltration.
  • This case underscores the diagnostic challenges of extramedullary plasmacytoma in the thyroid.

Implications:

  • Highlights the importance of comprehensive staging in suspected extramedullary plasmacytomas.
  • Emphasizes the need to consider MM even with initial negative results for systemic disease.
  • Informs diagnostic and treatment strategies for rare thyroid involvement in multiple myeloma.