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Sparganosis in a patient with diffuse large B cell lymphoma
Sang-Young Roh1, Jun Yong Lee, Kyun Woo Park
1Division of Medical Oncology, Seoul St. Mary's Hospital, Seoul, South Korea.
Journal of Cancer Research and Therapeutics
|February 13, 2014
Summary
Sparganosis, a human infection by tapeworm larvae, typically presents with subcutaneous nodules. This case suggests immunosuppression in lymphoma patients may influence sparganosis onset and severity.
Area of Science:
- Parasitology
- Immunology
- Oncology
Background:
- Sparganosis is a parasitic infection caused by tapeworm larvae (plerocercoids).
- Clinical presentation often includes subcutaneous nodules, with rare occurrences in the orbit, viscera, or breast.
- No prior reports linked sparganosis to patient immunocompromised status.
Observation:
- A case of sparganosis was observed in a patient diagnosed with lymphoma.
- The patient's immune system was suppressed due to ongoing anticancer therapy.
- Subcutaneous nodules were the primary clinical manifestation.
Findings:
- The patient presented with sparganosis during a period of immunosuppression.
- This case suggests a potential link between compromised immunity and the development or worsening of sparganosis.
- The parasitic infection manifested in a manner consistent with known sparganosis presentations.
Implications:
- Immunosuppression, particularly in cancer patients undergoing therapy, may predispose individuals to sparganosis.
- This finding warrants further investigation into the role of immune status in parasitic infections.
- Consideration of sparganosis in immunocompromised patients with relevant symptoms is recommended.
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