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Updated: May 3, 2026

An “All-laser” Endothelial Transplant
Published on: July 6, 2015
An innovative intrastromal keratoprosthesis surgery assisted by femtosecond laser
Jorge L Alio1, Alessandro Abbouda, Alfredo Vega-Estrada
1Division of Ophthalmology, Miguel Hernández University of Elche, Alicante - Spain.
Purpose:
To demonstrate the surgical application of a new model of epidescemetic keratoprosthesis.
Methods:
A 53-year-old man was referred to our center with severe alkali burns in both eyes and was treated by a combined corneal graft associated with KeraKlear implantation assisted by femtosecond laser and cataract surgery with implantation of an intraocular lens.
Results:
After 1 month, visual acuity was 0.6 logMAR in both eyes with -2 sphere correction. Slit-lamp examination and anterior segment optical coherence tomography revealed that the device was centered in the pupil area with no infection. No sign of extrusion was detected.
Conclusions:
The advantage of this device is that it involves nonperforating surgery, thus reducing the postoperative risk of infection and necrosis of tissue around the prosthesis. Large-scale studies with a long follow-up period are required to evaluate the outcome of use of this device.
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