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Updated: May 3, 2026
10:39
3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
Published on: June 2, 2014
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Abdominal migraine reviewed from both central and peripheral aspects
Yosuke Kakisaka1, Mitsugu Uematsu1, Zhong I Wang1
1Yosuke Kakisaka, Mitsugu Uematsu, Kazuhiro Haginoya, Department of Pediatrics, Tohoku University School of Medicine, Sendai, Miyagi 980-8574, Japan.
World Journal of Experimental Medicine
|February 13, 2014
Summary
Abdominal migraine (AM) in children, affecting 2%-5%, has an unknown mechanism. This review explores potential central and peripheral nervous system roles, citing cases with neurological symptoms and skin changes.
Area of Science:
- Neurology
- Pediatrics
- Gastroenterology
Background:
- Abdominal migraine (AM) affects 2%-5% of children, yet its underlying mechanism remains unclear.
- AM symptoms primarily manifest peripherally, but central nervous system involvement is suspected.
Purpose of the Study:
- To review recent studies on abdominal migraine (AM).
- To speculate on the mechanisms of AM, considering both peripheral and central nervous system (CNS) aspects.
Main Methods:
- Literature review of recent studies on abdominal migraine.
- Analysis of case reports suggesting CNS and peripheral nervous system involvement.
Main Results:
- Evidence suggests potential central nervous system dysfunction in AM, including photophobia, phonophobia, and abnormal visual evoked responses.
- Case reports highlight combined AM with "Alice in Wonderland" syndrome and peculiar ecchymosis, indicating possible CNS and peripheral nervous system links.
Conclusions:
- The hypothesized schema integrating peripheral and central nervous system factors provides a framework for future research into AM mechanisms.
- Further investigation and case accumulation are necessary to fully elucidate the pathophysiology of this condition.
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