Psoriasis: the visible killer

Tiago Torres1, Nuno Bettencourt2

  • 1Department of Dermatology, Centro Hospitalar do Porto, Porto, Portugal; Unit for Multidisciplinary Investigation in Biomedicine, Instituto de Ciências Biomédicas Abel Salazar - Universidade do Porto, Porto, Portugal.

Insights

Severe psoriasis patients face increased cardiovascular risks due to chronic inflammation. Early detection and multidisciplinary management of psoriasis and its comorbidities are crucial for preventing heart attacks and strokes.

Area of Science:

  • Dermatology
  • Cardiology
  • Immunology

Background:

  • Psoriasis is a chronic inflammatory skin condition linked to significant comorbidities.
  • Severe psoriasis is associated with increased mortality from cardiovascular diseases like myocardial infarction and stroke.
  • Patients with psoriasis exhibit a higher prevalence of traditional cardiovascular risk factors.

Purpose of the Study:

  • To emphasize the link between psoriasis's chronic inflammation and cardiovascular disease (CVD) risk.
  • To highlight the necessity of managing psoriasis comorbidities and CVD.
  • To advocate for effective psoriasis treatment to reduce systemic inflammation.

Main Methods:

  • Review of existing literature on psoriasis, comorbidities, and cardiovascular outcomes.
  • Analysis of the role of chronic inflammation in psoriasis-related CVD.
  • Discussion of multidisciplinary care strategies for severe psoriasis patients.

Main Results:

  • Chronic inflammation in psoriasis may be an independent risk factor for CVD.
  • Psoriasis patients have elevated rates of diabetes, hypertension, dyslipidemia, and obesity.
  • Effective psoriasis treatment can mitigate systemic inflammation and potentially lower CVD risk.

Conclusions:

  • Early identification and treatment of psoriasis comorbidities and CVD are essential.
  • A multidisciplinary approach is vital for optimizing the care of severe psoriasis patients.
  • Managing systemic inflammation in psoriasis is key to preventing cardiovascular events.

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