The Concise Guide to PHARMACOLOGY 2013/14: ion channels

Area of Science:

• Pharmacology
• Drug Discovery
• Biomedical Sciences

Background:

• The Concise Guide to Pharmacology is a key resource for understanding human drug targets.
• It categorizes targets into seven major groups, including ion channels and G protein-coupled receptors.
• The guide is produced in conjunction with NC-IUPHAR, providing official classifications.

Purpose of the Study:

• To provide concise overviews of over 2000 human drug targets and their pharmacology.
• To link to an open-access knowledgebase for more detailed information on drug targets and ligands.
• To offer nomenclature guidance and information on pharmacological tools.

Main Methods:

• Compilation of data on over 2000 human drug targets.
• Categorization of targets into seven major pharmacological classes.
• Presentation of information in a landscape format with comparative tables.

Main Results:

• Overviews of key properties for more than 2000 human drug targets.
• Links to an open-access knowledgebase (www.guidetopharmacology.org) for detailed target and ligand properties.
• Summary information on pharmacological tools, references, and further reading.

Conclusions:

• The 2013/14 Guide serves as a condensed, citable record of human drug target information.
• It consolidates data from previous resources and supersedes earlier guides.
• The linked website provides continuously updated and more detailed information.