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The sensitivity of domestic animal cell lines to eight recombinant human interferons
R Bridgman1, C R Rossi, M Campos
1Animal Health Research, Alabama Agricultural Experiment Station, Auburn.
Journal of Interferon Research
|February 1, 1988
Abstract:
The biological activities of eight recombinant human interferons (IFNs) were tested on permanent cell lines and low-passage embryonic cultures from domestic animal tissues. Each titer was compared to its titer on Madin-Darby bovine kidney (MDBK) cells. Although different cells within a species had different sensitivities to different IFNs, the order of sensitivity, in general, was ox, sheep, pig, cat, horse, and dog, the latter being quite insensitive to most IFNs.