IDO mutants cross resistant to type I interferon retain p91-dependent gene induction

S B Klein1, A Yeivin, G Becker

  • 1Department of Biology, Indiana University, Bloomington.

Journal of Interferon Research
|December 1, 1994
PubMed
Summary

Genetic analysis revealed p91 is crucial for interferon signaling. However, specific mutants suggest indoleamine 2,3-dioxygenase (IDO) induction involves distinct proteins, not directly linked to p91 activation.