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Author Spotlight: Development of Homogeneous κ-Carrageenan Sub-Microgel Baths for High-Resolution 3D Bioprinting
Published on: May 3, 2024
Carrageenan and its applications in drug delivery
Liang Li1, Rui Ni1, Yang Shao1
1School of Pharmacy, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang 110016, China.
Abstract:
Carrageenan is a sulphated linear polysaccharide of D-galactose and 3, 6-anhydro-D-galactose obtained by extraction of certain red seaweeds of the Rhodophyceae class. The objective of this review is to summarize recent applications of carrageenan in drug delivery systems. So far, carrageenan has been investigated as an excipient in pharmaceutical industry, for example, as polymer matrix in oral extended-release tablets, as a novel extrusion aid for the production of pellets and as a carrier/stabilizer in micro/nanoparticles systems. Moreover, based on the special characteristics of carrageenan such as the strong negative charge and gelling, it has been used as a gelling agent/viscosity enhancing agent for controlled drug release and prolonged retention. Furthermore, carrageenan has been used for tissue regeneration with therapeutic biomacromolecules and for cell delivery. Other potential applications and safety evaluation of carrageenan are still to be undertaken in the near future.
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