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A Pediatric Concussion Model in Mice: Closed Head Injury with Long-Term Disorders (CHILD)
Published on: February 7, 2025
Neuropsychiatry of pediatric traumatic brain injury
1Neuropsychiatric Research, Rady Children's Hospital, 3020 Children's Way, MC 5018, San Diego, CA 92123-4282, USA.
Insights
Pediatric traumatic brain injury (TBI) can lead to new psychiatric disorders (NPD) after injury. This review covers pre-existing conditions, risk factors, and treatments for these novel post-TBI psychiatric issues in children.
Area of Science:
- Neuroscience
- Child Psychiatry
- Public Health
Background:
- Pediatric traumatic brain injury (TBI) is a significant public health concern.
- Pre-existing psychiatric disorders are more prevalent in children with TBI than in the general population.
- Novel psychiatric disorders (NPD) emerging after TBI are common and impair child functioning.
Abstract:
Pediatric traumatic brain injury (TBI) is a major public health problem. Psychiatric disorders with onset before the injury are more common than population base rates. Novel (postinjury onset) psychiatric disorders (NPD) are also common and complicate child function after injury. Novel disorders include personality change due to TBI, secondary attention-deficit/hyperactivity disorder, other disruptive behavior disorders, and internalizing disorders. This article reviews preinjury psychiatric disorders as well as biopsychosocial risk factors and treatments for NPD.

