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Structural and genetic studies of the O-antigen of Enterobacter cloacae G2277

Andrei V Perepelov1, Min Wang2, Andrei V Filatov1

  • 1N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 119991 Moscow, Russian Federation.

Carbohydrate Research
|February 18, 2014
PubMed

Keywords:
Bacterial polysaccharide structureEnterobacter cloacaeLipopolysaccharideO-Antigen gene clusterO-Polysaccharide

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Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid...
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