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Updated: May 3, 2026

Author Spotlight: Advancements in Retroperitoneal Approach for Necrotizing Pancreatitis
Published on: March 15, 2024
[Timing and efficacy of surgical intervention for severe acute pancreatitis]
Jin Yang1, Qin-shu Shao2, Ji Xu
1Department of General Surgery, Zhejiang Provincial People's Hospital, Hangzhou 310014, China.
Objective:
To explore the indications, timing and approaches of surgical interventions for severe acute pancreatitis (SAP).
Methods:
A retrospective study was performed for 115 hospitalized SAP patients from 2007 to 2013.
Results:
Among them, 62 underwent surgery and another 53 were treated conservatively. The curative and mortality rates of surgical intervention and non-operation groups were 87.1%vs 84.9% (P > 0.05) and 9.68% vs 9.43% (P > 0.05) respectively. Twenty-five patients received early surgical intervention (<2 week) and another 37 delayed surgical intervention. The interval from diagnosis to surgical intervention of two groups were 7.5 ± 3.3 and 23.9 ± 8.5 days respectively. The mortality rates of early and delayed surgical groups were 16.0% and 5.4% respectively (P > 0.05).
Conclusions:
Individualized comprehensive therapy should be offered in the treatment of SAP. Timing of surgery for those with pancreatic necrosis and infection should be delayed to 3-4 weeks later until their general conditions permit.
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