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Related Concept Videos

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Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
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Related Experiment Video

Updated: May 3, 2026

Microsurgical Clip Obliteration of Middle Cerebral Aneurysm Using Intraoperative Flow Assessment
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Flow diversion for complex middle cerebral artery aneurysms.

Mario Zanaty1, Nohra Chalouhi, Stavropoula I Tjoumakaris

  • 1Department of Neurosurgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, PA, USA.

Neuroradiology
|February 19, 2014
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Summary
This summary is machine-generated.

Flow diversion using the Pipeline Embolization Device (PED) is a safe and effective treatment for complex middle cerebral artery (MCA) aneurysms, showing high occlusion rates and low complication rates.

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Area of Science:

  • Endovascular neurosurgery
  • Cerebrovascular disease management
  • Medical device technology

Background:

  • Large and complex middle cerebral artery (MCA) aneurysms pose significant treatment challenges.
  • Evaluating novel endovascular techniques is crucial for improving patient outcomes.

Purpose of the Study:

  • To assess the safety and efficacy of flow diversion for treating large and complex MCA aneurysms.
  • To determine the occlusion rates and complication profile of Pipeline Embolization Device (PED) use in this patient cohort.

Main Methods:

  • Retrospective review of patients treated with PED for MCA aneurysms between October 2010 and October 2013.
  • Inclusion of ten patients with large, giant, or bifurcation MCA aneurysms.
  • Analysis of angiographic and clinical follow-up data (7-12 months).

Main Results:

  • No technical complications or mortality were observed.
  • One periprocedural morbidity and one clinically significant thromboembolic event (in a patient off antiplatelet therapy).
  • Complete aneurysm occlusion was achieved in 7 out of 9 patients (78%) at follow-up.

Conclusions:

  • Pipeline Embolization Device (PED) treatment is a feasible option for large, giant, and bifurcation MCA aneurysms.
  • The technique demonstrates a satisfying complete occlusion rate with no mortality and a reasonable morbidity rate.
  • Flow diversion offers a promising endovascular solution for complex MCA aneurysms.