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Elevated alpha-fetoprotein in pregnancy complicated by aplasia cutis after exposure to methimazole

D Farine1, J Maidman, S Rubin

  • 1Department of Obstetrics and Gynecology, Columbia Presbyterian Medical Center, New York, New York.

Obstetrics and Gynecology
|June 1, 1988
PubMed

A case of aplasia cutis after exposure to methimazole (Tapazole) in early pregnancy is described. Elevated maternal serum alpha-fetoprotein (MSAFP) and amniotic fluid alpha-fetoprotein (AFP) were found. Elevated MSAFP and amniotic fluid AFP in women exposed to methimazole may suggest this rare fetal condition.

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