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War on terror cells: killing the host that harbours 'superbugs' is an infection control strategy in our fight against

Naveed Ahmed Khan, Ruqaiyyah Siddiqui

    Pathogens and Global Health
    |February 20, 2014
    PubMed

    Insights

    Targeting environmental hosts harboring antimicrobial-resistant bacteria, or

    Area of Science:

    • Microbiology and Environmental Science

    Background:

    • Antimicrobial resistance (AMR) poses a significant global health threat, driven by the proliferation of 'superbugs'.
    • Environmental reservoirs play a crucial role in the transmission and persistence of these multidrug-resistant organisms.

    Purpose of the Study:

    • To evaluate the efficacy of targeting environmental hosts as a novel strategy to combat infectious diseases caused by 'superbugs'.

    Main Methods:

    • This study proposes a conceptual framework for identifying and intervening in environmental reservoirs harboring 'superbugs'.

    Main Results:

    • The proposed strategy focuses on disrupting the environmental transmission pathways of antimicrobial-resistant pathogens.
    • Interventions in environmental hosts can potentially reduce the overall burden of infectious diseases.

    Conclusions:

    • Targeting environmental hosts represents a promising and effective approach to mitigate the spread of 'superbugs' and control infectious diseases.
    • This strategy complements traditional clinical interventions by addressing a key reservoir of antimicrobial resistance.
    Keywords:
    Antimicrobial resistanceInfectious diseases,Superbugs,

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