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Updated: May 2, 2026

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
Published on: December 11, 2016
The scale of repeat prescribing--time for an update
Duncan R Petty1, Arnold G Zermansky, David P Alldred
1School of Healthcare, University of Leeds, Leeds LS2 9UT, UK. d.petty@leeds.ac.uk.
Repeat prescriptions are common, with 43% of the population receiving them, and usage increases with age. The number of repeat prescription items has doubled in 20 years, impacting general practice and NHS costs.
Area of Science:
- Primary care
- Public health
- Health services research
Background:
- The National Health Service (NHS) faces significant annual costs from repeat prescriptions.
- Current data on the prevalence and patterns of repeat prescribing in primary care is outdated.
- Understanding repeat prescribing is crucial for effective service planning and policy development.
Purpose of the Study:
- To quantify the extent and demographic distribution of repeat prescribing in primary care.
- To analyze trends in repeat prescription item volume over time.
- To inform NHS service planning and policy related to medication management.
Main Methods:
- Anonymous data on prescription numbers and practice demographics were extracted from GP computer systems.
- Searches were conducted in November 2011 to determine repeat prescription items by age and sex.
- The proportion of repeat versus acute prescriptions was calculated.
Main Results:
- In the study year, 77% of 4,453,225 prescription items were repeats (mean 13 items/patient/annum).
- The mean number of repeat items per patient varied by age, from 0.45 (0-9 years) to 7.1 (80-89 years).
- 43% of the population received at least one repeat medicine, with over 75% of those aged 60+.
Conclusions:
- A substantial portion of the population relies on repeat prescriptions, with prevalence rising with age.
- While the ratio of repeat to acute items is stable, the volume of repeat prescription items has doubled in two decades.
- These trends have significant implications for general practice workload, patient convenience, healthcare costs, and medication safety.
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