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Implementation of a hospital deprescribing behaviour change intervention, the CompreHensive geriAtRician-led MEdication Review (CHARMER) trial: a process evaluation protocol.

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Updated: Jul 4, 2026

Functional Near-Infrared Spectroscopy Hyperscanning Study in Psychological Counseling
06:04

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Published on: January 17, 2025

Normalizing safe deprescribing: a qualitative study of primary care professionals' views using normalization process

Daniel A Okeowo1,2,3, Beth Fylan2,4, Syed T R Zaidi1,2,5

  • 1School of Healthcare, University of Leeds, Leeds, LS2 9JT, United Kingdom.

The International Journal of Pharmacy Practice
|July 2, 2026
PubMed
Summary

Implementing proactive deprescribing in primary care is challenging due to prescribing habits and safety concerns. Healthcare professionals (HCPs) emphasize structured guidelines and teamwork for safe and routine deprescribing.

Keywords:
Deprescribingmedicines optimizationnormalization process theorypolypharmacyprimary care

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Published on: January 17, 2025

Area of Science:

  • Primary Care Research
  • Health Services Research
  • Medication Management

Background:

  • Proactive deprescribing aims to reduce medication burden and harm.
  • Implementation in primary care faces challenges related to established prescribing practices and safety concerns.

Purpose of the Study:

  • To explore healthcare professionals' (HCPs) views on normalizing safe and routine deprescribing in English primary care.
  • To enhance understanding of proactive deprescribing implementation strategies.

Main Methods:

  • Qualitative study using interviews and focus groups with 30 primary care HCPs.
  • Data collected using an interview guide based on Normalization Process Theory.
  • Framework analysis applied to transcribed data to identify key themes.

Main Results:

  • Three themes emerged: the prescribing climate, routine implementation roles, and safety strategies.
  • Factors promoting prescribing over deprescribing were identified.
  • Patient and pharmacist roles, alongside safety measures, are crucial for routine deprescribing.

Conclusions:

  • Normalizing deprescribing is complex, influenced by prescribing habits, safety, and legal factors.
  • HCP confidence is shaped by experience; structured guidelines and teamwork are vital.
  • Clear protocols, expanded roles, and collaboration are essential for safe deprescribing implementation.