Ratiometric fluorescence assay for γ-glutamyltranspeptidase detection based on a single fluorophore via analyte-induced variation of substitution
Related Experiment Video
Updated: May 2, 2026
10:23
Glutamine Flux Imaging Using Genetically Encoded Sensors
Published on: July 31, 2014
9.0K
Xianfeng Hou1, Qingxiang Yu, Fang Zeng
1College of Materials Science & Engineering, State Key Lab of Luminescent Materials & Devices, South China University of Technology, Guangzhou 510640, P. R. China. mcfzeng@scut.edu.cn shzhwu@scut.edu.cn.
Chemical Communications (Cambridge, England)
|February 21, 2014
Abstract:
The first ratiometric fluorescent probe for γ-glutamyltranspeptidase (GGT) was developed, which functions through GGT-induced variation of substitution and subsequent changes in photophysical properties. It can detect GGT in human serum, and be used to visualize the endogenous GGT in ovarian cancer cells.
