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Demonstrating a Multi-drug Resistant Mycobacterium tuberculosis Amplification Microarray
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Potential for use of the Seegene Anyplex MTB/NTM real-time detection assay in a regional reference laboratory
Michael D Perry1, P Lewis White, Michael Ruddy
1Public Health Wales Microbiology Cardiff, University Hospital of Wales, Heath Park, Cardiff, United Kingdom.
Journal of Clinical Microbiology
|February 21, 2014
Abstract:
Requests for direct molecular diagnosis of mycobacterial disease are increasingly warranted. The Anyplex MTB/NTM assay demonstrates sensitivities, specificities, and positive and negative predictive values of 1.00, 0.96, 0.93, and 1.00 for Mycobacterium tuberculosis complex (MTBC) and 1.00, 0.97, 0.75, and 1.00 for nontuberculous mycobacteria (NTM) detection, respectively, making it a suitable screening test for mycobacterial detection.

