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Paediatric T cell Lymphoma with Nephrotic Syndrome: A Rare Association

Deepa Joseph1, Dubashi Biswajit2, Rajesh Nachiappa Ganesh3

  • 1Department of Radiation Oncology, RCC, JIPMER, Pondicherry, 605006 India.

Indian Journal of Hematology & Blood Transfusion : an Official Journal of Indian Society of Hematology and Blood Transfusion
|February 21, 2014
PubMed

Insights

Renal involvement is common in pediatric cancers. This case highlights a rare association between T cell lymphoma and nephrotic syndrome in a child.

Area of Science:

  • Pediatric Oncology
  • Nephrology
  • Hematology

Background:

  • Renal complications are common in pediatric malignancies, including Hodgkin's lymphoma.
  • Causes include tumor lysis syndrome, urinary tract obstruction, and glomerulopathies.
  • Nephrotic syndrome is rarely reported in pediatric T cell lymphoma.

Observation:

  • A 10-year-old boy presented with peripheral T cell lymphoma.
  • The patient also exhibited symptoms of nephrotic syndrome.

Findings:

  • This case describes an unusual co-occurrence of peripheral T cell lymphoma and nephrotic syndrome in a pediatric patient.
  • It underscores the diverse renal manifestations of hematologic malignancies.

Implications:

  • Highlights the importance of considering nephrotic syndrome in children diagnosed with T cell lymphoma.
  • Suggests further investigation into the mechanisms linking T cell lymphoma and nephrotic syndrome in pediatric cases.

Keywords:
Nephrotic syndromePTCLPediatric Lymphoma

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