The effect of chronic kidney disease on total hip arthroplasty
Alexander Miric1, Maria C S Inacio2, Robert S Namba3
1Southern California Permanente Medical Group, Department of Orthopaedic Surgery, Los Angeles, California.
Insights
Patients with chronic kidney disease (CKD) undergoing total hip arthroplasty (THA) face a higher risk of 90-day readmission. However, CKD did not significantly increase risks for revision surgery, infection, or mortality after THA.
Area of Science:
- Orthopedic Surgery
- Nephrology
- Public Health
Background:
- Chronic kidney disease (CKD) affects surgical outcomes.
- Total hip arthroplasty (THA) is a common procedure.
- Understanding risks for CKD patients undergoing THA is crucial.
Purpose of the Study:
- To evaluate the risks of revision, surgical site infection (SSI), thromboembolic events, mortality, and readmission in patients with CKD undergoing THA.
- To compare outcomes between CKD patients and those without CKD after THA.
Main Methods:
- Retrospective analysis of 20,720 primary THA cases.
- Identified 1269 patients (6.1%) with CKD.
- Adjusted for demographic and comorbidity factors.
Main Results:
- CKD patients had a 1.4-fold increased risk of 90-day readmission (95% CI 1.1-1.8).
- No significant differences in risks for revision (aseptic, septic), SSI (deep, superficial), deep vein thrombosis, pulmonary embolism, or mortality (30-day, 90-day, ever) were observed.
- CKD patients represent a distinct population requiring specific attention.
Conclusions:
- CKD is associated with an elevated risk of 90-day readmission following THA.
- CKD does not appear to significantly increase the risk of major complications like revision, infection, or mortality after THA.
- These findings highlight the need for targeted post-discharge care for CKD patients after THA.
Abstract:
Patients with chronic kidney disease (CKD) undergoing total hip arthroplasty (THA) were evaluated for risk of revision, surgical site infection (SSI), thromboembolic events, mortality and readmission. 20,720 primary TKA cases were included (smaller sample for readmission evaluation, N = 9322). The prevalence of CKD among THA patients was 6.1% (N = 1269). After adjustment for age, gender, race, general health, and diabetes, CKD patients were at 1.4 (95% confidence interval 1.1-1.8) increased risk of readmission within 90 days. The adjusted risks for revision (overall, aseptic, and septic), SSI (deep and superficial), deep vein thrombosis, pulmonary embolism, and mortality (30-day, 90-day, ever) were not significantly different between patients with CKD and those without CKD. However, increased risk for 90-day readmission underscores that CKD patients are a fundamentally different population of patients.
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