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Updated: May 2, 2026
06:55
Left Lung Orthotopic Transplantation in a Juvenile Porcine Model for ESLP
Published on: February 14, 2022
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Heart and lung transplantation.
Brigid Flynn1, Jonathan Hastie, Robert N Sladen
1Cardiothoracic Intensive Care Unit, Division of Critical Care Medicine, Department of Anesthesiology, Columbia University Medical Center, New York, New York, USA.
Current Opinion in Anaesthesiology
|February 22, 2014
Summary
Recent advancements in heart and lung transplantation include mechanical circulatory support and extracorporeal membrane oxygenation. Ongoing research focuses on optimizing immunosuppression and evaluating new techniques for improved patient outcomes.
Area of Science:
- Cardiology
- Thoracic Surgery
- Transplant Medicine
Background:
- Heart and lung transplantation are critical procedures performed globally.
- Continuous advancements in surgical techniques and medical management are evolving the field.
Purpose of the Study:
- To review recent changes and future directions in heart and lung transplantation.
- To present preoperative, intraoperative, and postoperative developments supported by evidence.
Main Methods:
- Literature review of recent advancements in heart and lung transplantation.
- Synthesis of evidence regarding evolving practices and technologies.
Main Results:
- Heart transplantation increasingly utilizes mechanical circulatory support for bridge-to-transplant and postoperative support.
- Lung transplantation sees expanded use of extracorporeal membrane oxygenation, lobar transplantation, and ex-vivo lung perfusion.
- Improved immunosuppression regimens are leading to decreased rejection rates in both heart and lung recipients.
Conclusions:
- Mechanical circulatory support and extracorporeal membrane oxygenation are integral to perioperative care in transplantation.
- Further research is needed to establish the safety profiles of these advanced technologies.
- Personalized immunosuppression strategies remain a key area of ongoing investigation for transplant recipients.
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